AFP and hepatocellular carcinoma: Laser confocal microscope observations revealed that in the normal human liver L-02 and CHL cell lines, p-mTOR(Ser2448) was located only in the cytoplasm, but p-mTOR(Ser2448) was located in the cytoplasm and nucleus of the AFP-producing and HBx-expressing malignant liver cell lines L-02-X, and CHL-X, and in HCC and PLC/PRF/5 cells.