Patients diagnosed with IgE-mediated food allergies can be given medications to reduce their symptoms.4, 5 These can be selected based on the involvement of IgE-mediated mast cell or basophil degranulation (antihistamines, antileukotrienes, epinephrine, anti-IgE), or T cells or eosinophil activation (steroids, anti-IL5) (Figure 3).3, 6 This procedure is beginning to enter clinical practice. This evidence concerns the gene IGHE and food allergy.