35.7% (25/70) of the subjects with CMV EOD/s in the CD4 range from 30–59 cells/μl had multisystem involvements of CMV diseases- 20.0% (14/70) had CMV induced GIT diseases along with retinitis, 14.3% (10/70) had CMV induced pulmonary diseases along with retinitis and 1.4% (1/70) had developed CMV induced Retinitis, GIT and Pulmonary diseases. This evidence concerns the gene CD4 and lung disorder.