Figure 1 depicts the prevalence of coronary calcium by genotype. Among RA patients with CC genotype, 75.7% had coronary calcium; as compared with 43.6% in those with CG genotype and with 37.5% in those with GG genotype (p = 0.001). However, in a post-hoc analysis examining the association of rs2073618 genotypes and serum osteoprotegerin concentrations, differences were non-significant [13]. (Median (interquartile range, IQR) concentrations were 1548 (1042–2509), 1497 (1100–1698), and 1657 (1132–2105) pg/mL, respectively, p = 0.38). This evidence concerns the gene TNFRSF11B and rheumatoid arthritis.