Conversely, fairly robust expansion of NP396 specific CD8+ T cell expansion was observed both in Ad-NP (~131 fold on day 10 post infection, 39 fold on day 60 post infection) and combined Ad-NP and Ad-IiGP vaccinated mice (~131 fold on day 10 post infection, 31 fold on day 60 post infection). Here, CD8A is linked to infection.