IFNA1 and viral infectious disease: The type I IFNs (which include multiple IFN-α subtypes and IFN-β) and the type III IFNs (IFN-λ) are directly upregulated following virus infection; these are the major IFNs secreted following influenza virus infections in vitro and in vivo (Crotta et al., 2013, Ioannidis et al., 2013, Jewell et al., 2010, Khaitov et al., 2009, Wang et al., 2009).