We used two mouse cancer cell lines stably transfected with human MUC1 cDNA, the lymphoma cell line RMA (RMA-MUC1) and the mouse ovarian cancer cell line IG10 (IG-10/MUC1), as well as the human colon cancer cell line Caco-2 that spontaneously expresses MUC1. Here, MUC1 is linked to malignant colon neoplasm.