Indeed, not only the number of tumor colonies and their size were reduced after treatment of mice with DACE, but also the amount of c-RAF-BxB protein and mRNA (Fig. 5D-G) and the measured amounts of tumor tissue correlated very well with the amounts of expressed human c-RAF-1-BxB protein and mRNA (Fig. 5F-5H). This evidence concerns the gene RAF1 and neoplasm.