As expected, epithelial genes known to be inactivated during EMT in breast cancer cells, such as Cdh1 (E-cadherin), Ocln (Occludin), Epcam, Cldn7 (Claudin 7), Id1, Krt7, Esr1, Cav2, Dsp, Gata3, and Cadm1 were among the downregulated genes. The gene discussed is ESR1; the disease is breast cancer.