In study conducted by Khalid et al. FVL mutation was detected in 14.2% patients that agree with current study.20 FVL mutation was detected in 1.3-4.3% of thrombophilia patients in earlier studies.26,27 There is marked heterogeneity in reported data about the frequency of FVL mutation in our population. The gene discussed is F5; the disease is Rare hereditary thrombophilia.