Furthermore, an albumin-binding minimal organic molecule [2-(3-maleimidopropanamido)-6-(4-(4-iodophenyl)butanamido) hexanoate] that has been chemically conjugated to a free cysteine residue engineered into the C-terminal end of an scFv fragment with tumor specificity, was shown to increase the half-life from 0.5 to 16.6 h in mice (250). This evidence concerns the gene ALB and neoplasm.