EGR1 and cancer: By examining a panel of human cell lines that were derived from a wide variety of cancer tissues, we found that they tend to fall into either of the steady states, miR-199(−)/Brm(+)/EGR1(−) cells and miR-199a(+)/Brm(−)/EGR1(+) cells17, denoted hereafter as type 1 and type 2, respectively.