EGR1 and cancer: Type 1-specific genes would be regulated in an all-or-none manner by either of these two feedforward loops that associate with the robust miR-199a/Brm/EGR1 axis that dictates cancer cell lines to either of the steady states, [miR-199(−)/Brm(+)/EGR1(−)] and [miR-199a(+)/Brm(−)/EGR(+)] (Fig. 6b).