B-cell lymphoma 2 (Bcl-2) family proteins regulate apoptosis in cancer progression, and they have been divided into pro- and anti-apoptotic groups, including Bcl-2, Bcl-extra large (xL), myeloid leukemia cell differentiation protein (Mcl-1), and Bcl-2 family proteins 1, 2 and 10 (6,7). Here, BCL2 is linked to cancer.