Conditional analysis showed that BTNL2 p.G454C remained significantly associated with IBD when the effect at the common UC associated SNP (rs477515) was accounted for (p = 0.0045, S6 Table), or the common CD associated SNP (rs9264942) was accounted for (p = 4.83x10−5, S6 Table). Here, BTNL2 is linked to inflammatory bowel disease.