As there is considerable evidence that genetic susceptibility can influence on tuberculosis acquisition risk, such as the higher susceptibility conferred by individual polymorphisms in genes for natural resistance-associated macrophage protein (NRAMP1), vitamin D receptor, or mannose-binding protein [47] [48], it has been suggested that different ethnic groups may have different susceptibility for particular M. tuberculosis strains [49]. This evidence concerns the gene SLC11A1 and tuberculosis.