In particular, ST7612AA1 was able to significantly inhibit tumor growth of the Ras-mutant HCT116 colon carcinoma xenografts, thus suggesting a putative therapeutic approach towards this subset of strongly proliferating dedifferentiated colorectal carcinoma, characterized by overexpression of class I HDAC family members and associated with reduced patient survival [22]. Here, HDAC9 is linked to colorectal carcinoma.