In particular, ST7612AA1 was able to significantly inhibit tumor growth of the Ras-mutant HCT116 colon carcinoma xenografts, thus suggesting a putative therapeutic approach towards this subset of strongly proliferating dedifferentiated colorectal carcinoma, characterized by overexpression of class I HDAC family members and associated with reduced patient survival [22]. This evidence concerns the gene HDAC9 and neoplasm.