Interestingly, at least when tested in vivo against colon carcinoma xenografts, ST7612AA1 induced increased transcription of e-cadherin, keratins and other typical epithelial markers and, concomitantly, induced down-regulation of vimentin and other genes associated to the mesenchymal phenotype, thus suggesting that treatment with ST7612AA1 might also cause a “cadherin switch” and reversion of the EMT process. This evidence concerns the gene VIM and colon carcinoma.