Additionally, CCL5 is critical for T-cellchemotaxis and infiltration as suggested by its receptor (C-C motif) receptor 5(CCR5) co-expressing with CXCR3 on CTLs in the invasive margin of colorectal tumors.The expression of both receptors has been linked with CTL infiltration and theabsence of metastasis [20-22]. Here, CCL5 is linked to colorectal neoplasm.