First, gender disparities in the care of acute stroke may be decreasing over time as the importance of time to treatment becomes more evident, and our data may reflect this.23 In addition, our findings suggest that the use of stroke triage protocols including nursing notifications of the arrival of acute stroke patients and a blast page system to indicate the arrival of tPA-eligible patients may decrease gender disparities in stroke care, though this will require investigation in future studies comparing EDs with stroke protocols to those without stroke protocols. This evidence concerns the gene PLAT and Stroke.