ERVW-1 and Epstein-Barr virus infection: It has been reported that the interaction between epithelial integrins (for example, αvβ6, αvβ8 or α5β1) and EBV envelope proteins (gHgL or BMRF2) is required for EBV infection of epithelial cells originated from tongue, nasopharyngeal and gastric carcinoma46, 47.