This hypothesis was also confirmed by the association of caprin-1 with G3BP1, c-Myc mRNA, and cyclins D1/D2 in polysomal fractions only in tylophorine- but not vehicle-treated carcinoma cells (Fig. 2D), whereas the c-Myc mRNA and cyclins D1/D2 mRNA levels were elevated in tylophorine-treated carcinoma cells (Fig. 2D-a and 3A). This evidence concerns the gene MYC and carcinoma.