In univariate analysis applied to the whole population (Table 2), axillary lymph node involvement, large tumor size, high grade, negative ER status, and negative PR status were associated with poor MFS, whereas PDL1 expression was not (p=0.57, Wald test; HR=0.94 [0.75-1.17], and p=0.576, log-rank test, Figure 2A). Here, ESR1 is linked to neoplasm.