In selecting the candidate regions, we chose known glaucoma genes (MYOC, WDR36 and CYP1B122), regions that have been identified in POAG association studies in other populations (the locus at chromosome 2p1623, CAV1/CAV224, CDKN2B/CDKN2B-AS125, 26, 27, TMCO125 and SIX1/SIX627, 28), candidate genes for central corneal thickness (CCT) (the collagen genes COL1A129, COL1A229, COL5A130, 31 and COL8A232 and the region of ZNF46930, 31) and candidate genes for optic nerve parameters (CDKN2B33, SIX1/SIX633 and ATOH733). This evidence concerns the gene SIX1 and open-angle glaucoma.