Together, these results indicate that CAD patients tend to have more CD14+ monocytes than normal controls, which suggests that the prospective mechanism for the increased release of urinary CD14 in CAD patients may be attributable to the up-regulation of CD14 mRNA expression resulting in higher expression of membrane-bound CD14 antigens on monocytes from CAD patients as compared to healthy controls. This evidence concerns the gene CD14 and coronary artery disorder.