TNF and myocardial ischemia: In the present study, therefore, an animal model of acute myocardial ischemia was established in rats by ligation of the coronary artery, in order to observe the effects of the H2S donor NaHS and the CSE inhibitor propargylglycine (PPG) on inflammatory cytokines, such as tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), IL-6 and nuclear factor κ-light-chain-enhancer of activated B cells (NF-κB), and intercellular adhesion molecule-1 (ICAM-1) in the presence of myocardial ischemia.