GPT and Cirrhosis: Although the differences between the AUC of sCD40 and ALT or sCD40 and AST were not statistically significant, the AUC of sCD40 was greater than the AUC of ALT and AST, when used to diagnose patients with CHB with moderate and marked inflammation (0.817 vs. 0.752 and 0.769, respectively), patients with marked inflammation (0.852 vs. 0.829 and 0.816, respectively) and patients with cirrhosis (0.799 vs. 0.694 and 0.709, respectively).