ABL1 and chronic myelogenous leukemia, BCR-ABL1 positive: It is characterized by a large accumulation of mature myeloid cells [4] and most CML patients demonstrate BCL-ABL1 fusion genes in hematopoietic progenitor cells, resulting from a reciprocal translocation between chromosomes 9 and 22, leading to a shortened chromosome 22, the Philadelphia (Ph) chromosome [2,5].