A common pattern emerged whereby patients that do not remit diabetes (T2D-NoR) displayed signifciantly higher expression levels for FGF21, HNF4α, CYP7A1, β-Klotho, GS, and FGFR4, compared to the No-T2D and T2D-R groups. Here, FGF21 is linked to type 2 diabetes mellitus.