However, by weeks 4 and 8 after infection, MGL1−/− mice produced significantly more IL-4 than the MGL1+/+ splenocytes in response to anti-CD3, whereas antigen-specific higher IL-4 production in MGL1−/− splenocytes was only observed at week 4 after infection compared with MGL1+/+ cells (Figures 6(b) and 6(c)). This evidence concerns the gene IL4 and infection.