In addition, Cox regression analysis demonstrated that the expression of active Cdk1 [odds ratio (OR), 0.624; 95% confidence ratio (CI), 0.400–0.973; P=0.038] and the pathological tumor-node-metastasis stage (OR, 0.515; 95% CI, 0.297–0.894; P=0.018) were significant independent prognostic factors for NSCLC. Here, CDK1 is linked to non-small cell lung carcinoma.