CDKN2A and cervical carcinoma: The mRNA and protein expression levels of P16, Cyclin D1 and pRb in SiHa and SiHa-DDP cell lines were detected, and p16 knock down of a SiHa-DDP cell line was performed to investigate the possible mechanism of DDP chemoresistance, which may lead to the development of novel treatment strategies for chemoresistant cervical carcinoma.