The prevalence and severity of albuminuria (p<0.0003), hyperphosphatemia (p<.0001), hyperparathyroidism (p<0.0001), and metabolic acidosis (p<0.0009) increased with decreasing eGFR, whereas serum albumin, 25OHD, and CRP were not statistically significantly associated with renal function. The gene discussed is ALB; the disease is hyperparathyroidism.