Pairwise comparisons showed significant differences only between the SCZ group versus the MDD, BD and controls groups (p = 5.52×10−7, p = 5.35×10−6 and p = 1.71×10−8, respectively), indicating that EGR1 mRNA level was upregulated only in SCZ PBCs (Fig. 2B). Here, EGR1 is linked to major depressive disorder.