IFNG and infection: To further confirm the observed phenotype of elevated dysregulated IFNγ responses in infected CD11ccreIFNγR2fl/fl mice was due to the selective impairment in Th1-Treg cell subset rather than the reduction of the entire Treg cell population, we first analyzed the group of CD11ccreIFNγR2fl/fl mice which retained similar frequencies of Treg cells as found in their corresponding WT littermates at day 8 post infection.