Amplification of EGFR SCNA was reported in colorectal cancer [40], esophageal cancer [41], glioblastomas [42], lung cancer [43], salivary gland cancer [44], and osteosarcoma [45]; taken together, these findings indicated that SCNA of EGFR is relatively common in cancer tissue. The gene discussed is EGFR; the disease is osteosarcoma.