Bottema et al. [18] investigated IL-13 polymorphisms in rhinitis and asthma populations; their results showed that IL-13 rs1800925 was significantly associated with rhinitis, while the polymorphisms of rs20541 and rs1295685 were consistently associated with asthma and serum IgE, which were consistent with the results of haplotypes. This evidence concerns the gene IL13 and asthma.