When CD11b+CD14+ cells were co-cultured with ovarian cancer cells, the invasion as well as the proliferation of cancer cells were robustly promoted and these promotions were almost completely inhibited by the pretreatment with anti-IL-6R antibody, while anti-IL-6R antibody did not affect ovarian cancer cell invasion and proliferation without CD11b+CD14+ cells, indicating that TAMs enhance ovarian cancer proliferation or invasion by secreting a certain amount of IL-6. The gene discussed is ITGAM; the disease is ovarian cancer.