From ovarian cancer ascites, CD11b-, CD11b+CD14- and CD11b+CD14+ cells were isolated and we found that CD11b+CD14+ cells expressed significantly high levels of IL-6 compared with other populations of cells and FACS analyses revealed that approximately 90% of CD11b+CD14+ were mannose receptor, CD206 positive, indicating that these populations of cells are predominantly M2-polarized macrophages, TAMs. The gene discussed is MRC1; the disease is ovarian cancer.