NOTCH4 and cancer: Looking specifically at the promoters (<1.5 Kb from the transcriptional start site) and 5’ and 3’ UTR regions proposed to be involved in transcriptional regulation, we found that 15 SNPs were located in putative promoter regions for 9 different coding genes (MDM4, PIK3C2B, MLPH, VAMP8, NOTCH4, MSMB, MMP7, NGFR, VPS53) and one non-coding gene, cancer susceptibility candidate 8 (CASC8).