Moreover, the PLCE1 rs2274223 A>G polymorphism was found to significantly increase stomach cancer risk under the homozygous model (AG vs. AA: adjusted OR = 1.48, 95% CI = 1.15–1.90), and dominant model (AG/GG vs. AA: adjusted OR = 1.45, 95% CI = 1.14–1.84). Here, PLCE1 is linked to gastric neoplasm.