The importance of WIP1 in human cancers is evident from the fact that it is amplified and overexpressed in primary breast tumors [15–17], gastric carcinomas [18], medulloblastoma [19–21], neuroblastoma [22], ovarian clear cell adenocarcinomas [23,24] and pancreatic adenocarcinomas [25]. The gene discussed is PPM1D; the disease is cancer.