Previously we demonstrated that at late times in SFV infection, when most of the infection-induced SG have been disassembled, SGs cannot be re-induced with phospho-eIF2α- or eIF4A-dependent stress inducers (sodium arsenite or pateamine A (Pat A), respectively) because G3BP is sequestered by nsP3 [28,29]. This evidence concerns the gene SH2D3C and infection.