Furthermore, participants with hypertension had a higher proportion with a positive family history of hypertension, had more often a low education level (P<0.01), a higher alcohol intake, a higher BMI, a lower eGFR and were more dyslipidemic and dysmetabolic and had higher serum concentrations of NT-proBNP (P<0.001). This evidence concerns the gene NPPB and Hypertension.