Logistic regression analysis showed that hypermethylated NTSR1, SLC5A8, GALR1, and AGTR1 and hypomethylated ZMYND10 were significantly associated with the NSCLC when risk-adjusted for age, sex and smoking status with the P value of 5.9 × 10-7, 7.8 × 10-9, 2.3 × 10-6, 1.3 × 10-6, and 5.2 × 10-8, respectively (Table 2). Here, SLC5A8 is linked to non-small cell lung carcinoma.