Although NBIA syndromes are rare genetic disorders with classic Mendelian inheritance (mostly autosomal Recessive type), some pathologic mutations in NBIA genes have been reported in rare monogenic Mendelian inheritance cases of Parkinson disease like ATP13A2 and PLA2G6 gene that are assigned respectively as PARK9 and PARK14 gene. This evidence concerns the gene PLA2G6 and hereditary disease.