HLA-B and toxic epidermal necrolysis: Further, the serotype HLA-B75 family, such as HLA-B*15:08, HLA-B*15:11 (0.25%, n = 5), HLA-B*15:18 (0.15%, n = 3) and HLA-B*15:21 (0.15%, n = 3), is associated with carbamazepine-induced SJS/TEN (Daly and Day, 2009; Lin et al., 2009).