GALC and Krabbe disease: The other example is Globoid cell leukodystrophy (also known as Krabbe’s disease), which is an autosomal recessively inherited disease caused by a deficiency of galactocerebrosidase (GALC), a lysosomal enzyme that degrades galactosylceramide, a major glycolipid component of myelin and myelin-forming cells (Katona et al. 2008).