Nine of the IHC 2+ tumors had a HER2/CEP17 ratio of more than 2.0, 18 IHC 2+ tumor samples had a HER2/CEP17 ratio between 1.5 and 2.0, while the remaining 5 IHC 2+ tumor samples had a HER2/CEP17 ratio below 1.5. The gene discussed is ERBB2; the disease is neoplasm.