Khani et al in their study about soy phytoestrogen (Genistein) effects on PCOS women found although HDL and FSH serum levels in Genistein and placebo group before and after treatment didn’t show any significant differences; but LH, TG, LDL, DHEAS, and testosterone levels were significantly decreased in case group. Here, PLOD1 is linked to polycystic ovary syndrome.