The results on sex, obesity (BMI or waist-hip ratio (WHR, i.e. the ratio of body circumferences at the waist and the hip)), blood pressure, plasma lipids (cholesterol and triglycerides), HbA1c, C-reactive protein (CRP) smoking, alcohol intake and cardiorespiratory fitness in age-stratified groups, are shown in Table 1. The gene discussed is CRP; the disease is obesity due to melanocortin 4 receptor deficiency.