BRCA1 and esophageal squamous cell carcinoma: Indeed, overexpression of miR-638 enhanced the proliferative, migratory and clonogenic properties of melanoma cells both in vitro and metastatic capacities in vivo. In line with our findings, miR-638 was shown to suppress BRCA1 and enhance the growth of esophageal squamous cell carcinoma cells [20].