Mutations in SAG, which is required for terminating rhodopsin activation, are primarily associated with Oguchi disease-1 (Maw et al., 1998; Nakamura et al., 2004; Waheed et al., 2012), but some mutations can cause an RP phenotype (Nakazawa et al., 1998). This evidence concerns the gene RHO and retinitis pigmentosa 1.